JAK1 - VAMP2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)
VAMP2	ENSG00000220205	No diseases in record	BOTULINUM TOXIN TYPE B	SNARE binding SNAP receptor activity protein binding calmodulin binding phospholipid binding syntaxin-1 binding syntaxin binding protein self-association calcium-dependent protein binding	SNC1 (S. cerevisiae) SNC2 (S. cerevisiae) snb-1 (C. elegans) Syb (D. melanogaster) nSyb (D. melanogaster)