ABL2 - JAK1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ABL2	ENSG00000143322	AML	No drugs in record	magnesium ion binding actin monomer binding protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding manganese ion binding actin filament binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)