JAK1 - PTPN1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)
PTPN1	ENSG00000196396	No diseases in record	No drugs in record	protein tyrosine phosphatase activity insulin receptor binding protein binding zinc ion binding enzyme binding protein kinase binding receptor tyrosine kinase binding ephrin receptor binding protein phosphatase 2A binding cadherin binding involved in cell-cell adhesion	Ptp61F (D. melanogaster)