CREBBP - KCNH2

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CREBBP	ENSG00000005339	ALL AML DLBCL B-NHL	No drugs in record	core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding RNA polymerase II activating transcription factor binding RNA polymerase II transcription coactivator activity transcriptional repressor activity, RNA polymerase II transcription factor binding p53 binding chromatin binding damaged DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity histone acetyltransferase activity signal transducer activity protein binding transcription factor binding zinc ion binding acetyltransferase activity peptide N-acetyltransferase activity MRF binding	BDF1 (S. cerevisiae) BDF2 (S. cerevisiae) nej (D. melanogaster)
KCNH2	ENSG00000055118	No diseases in record	AMIODARONE DALFAMPRIDINE DOFETILIDE GUANIDINE IBUTILIDE SOTALOL	phosphorelay sensor kinase activity inward rectifier potassium channel activity voltage-gated potassium channel activity delayed rectifier potassium channel activity protein binding ubiquitin protein ligase binding identical protein binding protein homodimerization activity C3HC4-type RING finger domain binding voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization scaffold protein binding voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	No GO terms in record