KCNH2 - EP300

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KCNH2	ENSG00000055118	No diseases in record	AMIODARONE DALFAMPRIDINE DOFETILIDE GUANIDINE IBUTILIDE SOTALOL	phosphorelay sensor kinase activity inward rectifier potassium channel activity voltage-gated potassium channel activity delayed rectifier potassium channel activity protein binding ubiquitin protein ligase binding identical protein binding protein homodimerization activity C3HC4-type RING finger domain binding voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization scaffold protein binding voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	No GO terms in record
EP300	ENSG00000100393	colorectal breast pancreatic AML ALL DLBCL	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding core promoter binding RNA polymerase II activating transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding p53 binding DNA binding chromatin binding damaged DNA binding transcription coactivator activity histone acetyltransferase activity lysine N-acetyltransferase activity, acting on acetyl phosphate as donor protein binding beta-catenin binding protein C-terminus binding transcription factor binding zinc ion binding acetyltransferase activity transferase activity, transferring acyl groups chromatin DNA binding activating transcription factor binding peptide N-acetyltransferase activity nuclear hormone receptor binding androgen receptor binding pre-mRNA intronic binding	BDF1 (S. cerevisiae) BDF2 (S. cerevisiae) nej (D. melanogaster)