SMAD3 - INSR

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SMAD3	ENSG00000166949	colorectal carcinoma oral squamous cell carcinoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter sequence-specific core promoter proximal region sequence-specific DNA binding RNA polymerase II activating transcription factor binding transcription factor activity, sequence-specific DNA binding transforming growth factor beta receptor binding protein binding collagen binding beta-catenin binding transcription factor binding zinc ion binding protein kinase binding phosphatase binding transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity chromatin DNA binding ubiquitin protein ligase binding enhancer binding identical protein binding protein homodimerization activity ubiquitin binding bHLH transcription factor binding sequence-specific DNA binding transcription regulatory region DNA binding protein heterodimerization activity co-SMAD binding R-SMAD binding transcription factor activity, protein binding	sma-3 (C. elegans) sma-2 (C. elegans)
INSR	ENSG00000171105	No diseases in record	INSULIN ASPART INSULIN ASPART PROTAMINE RECOMBINANT INSULIN DETEMIR INSULIN GLARGINE INSULIN GLULISINE INSULIN HUMAN INSULIN LISPRO INSULIN LISPRO PROTAMINE RECOMBINANT INSULIN PORK INSULIN PURIFIED BEEF INSULIN PURIFIED PORK INSULIN SUSP ISOPHANE BEEF INSULIN SUSP ISOPHANE BEEF/PORK INSULIN SUSP ISOPHANE PURIFIED BEEF INSULIN SUSP ISOPHANE PURIFIED PORK INSULIN SUSP ISOPHANE RECOMBINANT HUMAN INSULIN SUSP ISOPHANE SEMISYNTHETIC PURIFIED HUMAN INSULIN SUSP PROTAMINE ZINC BEEF/PORK INSULIN SUSP PROTAMINE ZINC PURIFIED BEEF INSULIN SUSP PROTAMINE ZINC PURIFIED PORK INSULIN ZINC SUSP BEEF INSULIN ZINC SUSP EXTENDED BEEF INSULIN ZINC SUSP EXTENDED PURIFIED BEEF INSULIN ZINC SUSP EXTENDED RECOMBINANT HUMAN INSULIN ZINC SUSP PROMPT BEEF INSULIN ZINC SUSP PROMPT PURIFIED PORK INSULIN ZINC SUSP PURIFIED BEEF INSULIN ZINC SUSP PURIFIED BEEF/PORK INSULIN ZINC SUSP PURIFIED PORK INSULIN ZINC SUSP RECOMBINANT HUMAN INSULIN ZINC SUSP SEMISYNTHETIC PURIFIED HUMAN	protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity insulin-activated receptor activity insulin-like growth factor receptor binding protein binding ATP binding GTP binding insulin-like growth factor I binding insulin-like growth factor II binding phosphatidylinositol 3-kinase binding insulin binding insulin receptor substrate binding PTB domain binding	daf-2 (C. elegans)