FGFR1 - IRS1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FGFR1	ENSG00000077782	MPN NHL salivary adenoma	LENVATINIB NINTEDANIB PAZOPANIB PONATINIB REGORAFENIB	protein tyrosine kinase activity fibroblast growth factor-activated receptor activity Ras guanyl-nucleotide exchange factor activity protein binding ATP binding heparin binding 1-phosphatidylinositol-3-kinase activity fibroblast growth factor binding identical protein binding protein homodimerization activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity	egl-15 (C. elegans) htl (D. melanogaster)
IRS1	ENSG00000169047	No diseases in record	No drugs in record	signal transducer activity transmembrane receptor protein tyrosine kinase adaptor activity protein kinase C binding Ras guanyl-nucleotide exchange factor activity insulin receptor binding insulin-like growth factor receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH2 domain binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity tRNA binding aminoacyl-tRNA editing activity ATP binding isoleucine-tRNA ligase activity	chico (D. melanogaster)