PROX1 - IRS1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PROX1	ENSG00000117707	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding transcription corepressor activity protein binding ligand-dependent nuclear receptor binding transcription regulatory region DNA binding DBD domain binding LBD domain binding	pros-1 (C. elegans) pros (D. melanogaster)
IRS1	ENSG00000169047	No diseases in record	No drugs in record	signal transducer activity transmembrane receptor protein tyrosine kinase adaptor activity protein kinase C binding Ras guanyl-nucleotide exchange factor activity insulin receptor binding insulin-like growth factor receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH2 domain binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity tRNA binding aminoacyl-tRNA editing activity ATP binding isoleucine-tRNA ligase activity	chico (D. melanogaster)