NFE2L2 - IRS1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
NFE2L2	ENSG00000116044	NSCLC HNSCC	No drugs in record	transcription regulatory region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II activating transcription factor binding transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding transcription cofactor binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein domain specific binding transcription regulatory region DNA binding	cnc (D. melanogaster)
IRS1	ENSG00000169047	No diseases in record	No drugs in record	signal transducer activity transmembrane receptor protein tyrosine kinase adaptor activity protein kinase C binding Ras guanyl-nucleotide exchange factor activity insulin receptor binding insulin-like growth factor receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH2 domain binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity tRNA binding aminoacyl-tRNA editing activity ATP binding isoleucine-tRNA ligase activity	chico (D. melanogaster)