KDM1A - NSD1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KDM1A	ENSG00000004487	No diseases in record	No drugs in record	RNA polymerase II transcription factor binding p53 binding chromatin binding transcription factor activity, sequence-specific DNA binding histone deacetylase activity protein binding transcription factor binding oxidoreductase activity enzyme binding ligand-dependent nuclear receptor transcription coactivator activity demethylase activity histone demethylase activity histone demethylase activity (H3-K4 specific) histone demethylase activity (H3-K9 specific) histone demethylase activity (H3-dimethyl-K4 specific) telomeric DNA binding MRF binding transcription regulatory region DNA binding flavin adenine dinucleotide binding androgen receptor binding telomeric repeat-containing RNA binding	Su(var)3-3 (D. melanogaster)
NSD1	ENSG00000165671	AML	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding chromatin binding transcription cofactor activity transcription corepressor activity zinc ion binding histone-lysine N-methyltransferase activity estrogen receptor binding histone methyltransferase activity (H4-K20 specific) retinoic acid receptor binding retinoid X receptor binding thyroid hormone receptor binding histone methyltransferase activity (H3-K36 specific) androgen receptor binding	SET2 (S. cerevisiae)