GRB2 - IDH2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
GRB2	ENSG00000177885	No diseases in record	No drugs in record	phosphotyrosine residue binding SH3/SH2 adaptor activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding neurotrophin TRKA receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH3 domain binding protein kinase binding protein phosphatase binding identical protein binding insulin receptor substrate binding ephrin receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	sem-5 (C. elegans)
IDH2	ENSG00000182054	glioblastoma	No drugs in record	magnesium ion binding isocitrate dehydrogenase (NADP+) activity NAD binding isocitrate dehydrogenase (NAD+) activity catalytic activity metal ion binding oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor RNA binding	IDP1 (S. cerevisiae) IDP2 (S. cerevisiae) IDP3 (S. cerevisiae)