ETV6 - GRB2

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ETV6 ENSG00000139083 congenital fibrosarcoma
multiple different leukaemia and lymphoma tumour types including ALL
secretory breast
MDS

No drugs in record

RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein domain specific binding
aop (D. melanogaster)
GRB2 ENSG00000177885

No diseases in record

No drugs in record

phosphotyrosine residue binding
SH3/SH2 adaptor activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
neurotrophin TRKA receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
SH3 domain binding
protein kinase binding
protein phosphatase binding
identical protein binding
insulin receptor substrate binding
ephrin receptor binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
sem-5 (C. elegans)