E2F2 - GRB2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
E2F2	ENSG00000007968	No diseases in record	No drugs in record	core promoter binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein dimerization activity protein heterodimerization activity transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II regulatory region DNA binding	E2f1 (D. melanogaster)
GRB2	ENSG00000177885	No diseases in record	No drugs in record	phosphotyrosine residue binding SH3/SH2 adaptor activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding neurotrophin TRKA receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH3 domain binding protein kinase binding protein phosphatase binding identical protein binding insulin receptor substrate binding ephrin receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	sem-5 (C. elegans)