ALK - GRB2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ALK	ENSG00000171094	ALCL NSCLC neuroblastoma inflammatory myofibroblastic tumour Spitzoid tumour	CERITINIB CRIZOTINIB	NF-kappaB-inducing kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity protein binding ATP binding identical protein binding	scd-2 (C. elegans)
GRB2	ENSG00000177885	No diseases in record	No drugs in record	phosphotyrosine residue binding SH3/SH2 adaptor activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding neurotrophin TRKA receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH3 domain binding protein kinase binding protein phosphatase binding identical protein binding insulin receptor substrate binding ephrin receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	sem-5 (C. elegans)