ADAM17 - GRB2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ADAM17	ENSG00000151694	No diseases in record	No drugs in record	metalloendopeptidase activity Notch binding interleukin-6 receptor binding integrin binding protein binding metallopeptidase activity SH3 domain binding PDZ domain binding metal ion binding	Tace (D. melanogaster)
GRB2	ENSG00000177885	No diseases in record	No drugs in record	phosphotyrosine residue binding SH3/SH2 adaptor activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding neurotrophin TRKA receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH3 domain binding protein kinase binding protein phosphatase binding identical protein binding insulin receptor substrate binding ephrin receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	sem-5 (C. elegans)