LEF1 - CTNNB1

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
LEF1	ENSG00000138795	B-ALL T-ALL eyelid sebaceous carcinoma AML lymphomas	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding beta-catenin binding transcription factor binding DNA binding, bending estrogen receptor activity estrogen receptor binding enhancer binding histone binding histone deacetylase binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process sequence-specific DNA binding transcription regulatory region DNA binding gamma-catenin binding armadillo repeat domain binding C2H2 zinc finger domain binding	pop-1 (C. elegans) pan (D. melanogaster)
CTNNB1	ENSG00000168036	colorectal ovarian hepatoblastoma pleomorphic salivary gland adenoma other tumour types	No drugs in record	RNA polymerase II transcription factor binding RNA polymerase II activating transcription factor binding double-stranded DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity signal transducer activity protein binding protein C-terminus binding transcription factor binding enzyme binding kinase binding protein kinase binding protein phosphatase binding estrogen receptor binding nuclear hormone receptor binding transcription regulatory region DNA binding ion channel binding alpha-catenin binding cadherin binding SMAD binding protein heterodimerization activity androgen receptor binding I-SMAD binding repressing transcription factor binding cadherin binding involved in cell-cell adhesion euchromatin binding	bar-1 (C. elegans) hmp-2 (C. elegans) arm (D. melanogaster)