IRS1 - MTOR

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
IRS1	ENSG00000169047	No diseases in record	No drugs in record	signal transducer activity transmembrane receptor protein tyrosine kinase adaptor activity protein kinase C binding Ras guanyl-nucleotide exchange factor activity insulin receptor binding insulin-like growth factor receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH2 domain binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity tRNA binding aminoacyl-tRNA editing activity ATP binding isoleucine-tRNA ligase activity	chico (D. melanogaster)
MTOR	ENSG00000198793	endometrial carcinoma head and neck clear cell renal cell carcinoma anaplastic thyroid cancer urothelial cell carcinoma central nervous system tumours testicular germ cell tumours and other tumour types	No drugs in record	RNA polymerase III type 1 promoter DNA binding RNA polymerase III type 2 promoter DNA binding RNA polymerase III type 3 promoter DNA binding TFIIIC-class transcription factor binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity protein kinase binding protein domain specific binding ribosome binding phosphoprotein binding ribonucleoprotein complex binding chromatin DNA binding nucleocytoplasmic transporter activity	TOR2 (S. cerevisiae) Tor (D. melanogaster)