SNX1 - PTPN11

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SNX1	ENSG00000028528	No diseases in record	No drugs in record	epidermal growth factor receptor binding insulin receptor binding protein binding phosphatidylinositol binding identical protein binding protein homodimerization activity protein heterodimerization activity cadherin binding involved in cell-cell adhesion transferrin receptor binding leptin receptor binding protein transporter activity phosphatidylinositol-3-phosphate binding	VPS5 (S. cerevisiae) snx-1 (C. elegans) Snx1 (D. melanogaster)
PTPN11	ENSG00000179295	JMML AML MDS	No drugs in record	phosphoprotein phosphatase activity protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity SH3/SH2 adaptor activity insulin receptor binding protein binding 1-phosphatidylinositol-3-kinase activity protein domain specific binding receptor tyrosine kinase binding D1 dopamine receptor binding phospholipase binding insulin receptor substrate binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity cell adhesion molecule binding peptide hormone receptor binding	PTP1 (S. cerevisiae) ptp-2 (C. elegans) csw (D. melanogaster)