CHD8 - SMAD7

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CHD8	ENSG00000100888	No diseases in record	No drugs in record	p53 binding DNA binding DNA helicase activity chromatin binding protein binding ATP binding beta-catenin binding DNA-dependent ATPase activity methylated histone binding histone binding armadillo repeat domain binding	CHD1 (S. cerevisiae) chd-7 (C. elegans)
SMAD7	ENSG00000101665	No diseases in record	No drugs in record	transcription factor activity, sequence-specific DNA binding protein binding collagen binding beta-catenin binding transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity ubiquitin protein ligase binding type I transforming growth factor beta receptor binding transcription regulatory region DNA binding metal ion binding activin binding I-SMAD binding	daf-14 (C. elegans) daf-8 (C. elegans) Dad (D. melanogaster)