FOXO3 - TRIM24

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FOXO3	ENSG00000118689	AL	No drugs in record	core promoter binding transcription cofactor binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding beta-catenin binding protein kinase binding chromatin DNA binding sequence-specific DNA binding	HCM1 (S. cerevisiae) daf-16 (C. elegans) foxo (D. melanogaster)
TRIM24	ENSG00000122779	APL	No drugs in record	p53 binding chromatin binding transcription coactivator activity protein tyrosine kinase activity ubiquitin-protein transferase activity receptor binding protein binding zinc ion binding ligase activity ligand-dependent nuclear receptor binding estrogen response element binding sequence-specific DNA binding ubiquitin protein ligase activity lysine-acetylated histone binding methylated histone binding	bon (D. melanogaster)