FOXO3 - AIRE

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FOXO3	ENSG00000118689	AL	No drugs in record	core promoter binding transcription cofactor binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding beta-catenin binding protein kinase binding chromatin DNA binding sequence-specific DNA binding	HCM1 (S. cerevisiae) daf-16 (C. elegans) foxo (D. melanogaster)
AIRE	ENSG00000160224	No diseases in record	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding transcription cofactor activity protein binding zinc ion binding histone binding identical protein binding transcription regulatory region DNA binding translation regulator activity	bon (D. melanogaster)