RAC1 - KDM6A

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAC1	ENSG00000136238	melanoma carcinoma	No drugs in record	GTPase activity protein binding GTP binding Rab GTPase binding enzyme binding protein kinase binding GTP-dependent protein binding thioesterase binding histone deacetylase binding Rho GDP-dissociation inhibitor binding GTPase activating protein binding	CDC42 (S. cerevisiae) rac-2 (C. elegans) Rac1 (D. melanogaster) Rac2 (D. melanogaster)
KDM6A	ENSG00000147050	renal cell carcinoma bladder carcinoma oesophageal SCC MM medulloblastoma T-ALL other tumour types	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding chromatin DNA binding histone demethylase activity identical protein binding metal ion binding dioxygenase activity histone demethylase activity (H3-K27 specific)	CYC8 (S. cerevisiae) Utx (D. melanogaster)