CDKN1B - JAK1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDKN1B	ENSG00000111276	breast small intestine neuroendocrine tumours pituitary parathyroid	No drugs in record	cyclin-dependent protein serine/threonine kinase inhibitor activity transforming growth factor beta receptor, cytoplasmic mediator activity protein binding protein phosphatase binding Hsp70 protein binding protein complex binding chaperone binding cysteine-type endopeptidase activator activity involved in apoptotic process	No GO terms in record
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)