HDAC6 - E2F1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HDAC6	ENSG00000094631	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	core promoter binding actin binding histone deacetylase activity protein binding beta-catenin binding microtubule binding zinc ion binding enzyme binding polyubiquitin binding ubiquitin protein ligase binding NAD-dependent histone deacetylase activity (H3-K14 specific) histone deacetylase binding tubulin deacetylase activity alpha-tubulin binding tau protein binding beta-tubulin binding misfolded protein binding Hsp90 protein binding dynein complex binding deacetylase activity	HDA1 (S. cerevisiae) hda-6 (C. elegans) HDAC6 (D. melanogaster)
E2F1	ENSG00000101412	No diseases in record	No drugs in record	core promoter binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein kinase binding sequence-specific DNA binding protein dimerization activity RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II regulatory region DNA binding	E2f1 (D. melanogaster)