HDAC6 - CASP3

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HDAC6	ENSG00000094631	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	core promoter binding actin binding histone deacetylase activity protein binding beta-catenin binding microtubule binding zinc ion binding enzyme binding polyubiquitin binding ubiquitin protein ligase binding NAD-dependent histone deacetylase activity (H3-K14 specific) histone deacetylase binding tubulin deacetylase activity alpha-tubulin binding tau protein binding beta-tubulin binding misfolded protein binding Hsp90 protein binding dynein complex binding deacetylase activity	HDA1 (S. cerevisiae) hda-6 (C. elegans) HDAC6 (D. melanogaster)
CASP3	ENSG00000164305	No diseases in record	No drugs in record	protease binding aspartic-type endopeptidase activity cysteine-type endopeptidase activity death receptor binding protein binding peptidase activity cysteine-type endopeptidase activator activity involved in apoptotic process phospholipase A2 activator activity protein complex binding cysteine-type endopeptidase activity involved in apoptotic process cysteine-type endopeptidase activity involved in execution phase of apoptosis	Drice (D. melanogaster) Dcp-1 (D. melanogaster)