HDAC6 - NCK1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HDAC6	ENSG00000094631	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	core promoter binding actin binding histone deacetylase activity protein binding beta-catenin binding microtubule binding zinc ion binding enzyme binding polyubiquitin binding ubiquitin protein ligase binding NAD-dependent histone deacetylase activity (H3-K14 specific) histone deacetylase binding tubulin deacetylase activity alpha-tubulin binding tau protein binding beta-tubulin binding misfolded protein binding Hsp90 protein binding dynein complex binding deacetylase activity	HDA1 (S. cerevisiae) hda-6 (C. elegans) HDAC6 (D. melanogaster)
NCK1	ENSG00000158092	No diseases in record	No drugs in record	protein kinase inhibitor activity SH3/SH2 adaptor activity ARF guanyl-nucleotide exchange factor activity receptor binding protein binding cytoskeletal adaptor activity protein domain specific binding receptor signaling complex scaffold activity protein binding, bridging receptor tyrosine kinase binding ephrin receptor binding eukaryotic initiation factor eIF2 binding cadherin binding involved in cell-cell adhesion	nck-1 (C. elegans) dock (D. melanogaster)