FBXW7 - HMGA1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FBXW7	ENSG00000109670	colorectal endometrial T-ALL	No drugs in record	ubiquitin-protein transferase activity protein binding cyclin binding protein binding, bridging ubiquitin protein ligase binding identical protein binding phosphothreonine residue binding ubiquitin-protein transferase activator activity	MET30 (S. cerevisiae) sel-10 (C. elegans) ago (D. melanogaster)
HMGA1	ENSG00000137309	microfollicular thyroid adenoma various benign mesenchymal tumours	No drugs in record	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding DNA binding AT DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding enzyme binding ligand-dependent nuclear receptor transcription coactivator activity retinoic acid receptor binding peroxisome proliferator activated receptor binding retinoid X receptor binding	No GO terms in record