BUB1B - NSD1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BUB1B	ENSG00000156970	rhabdomyosarcoma	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein binding ATP binding	BUB1 (S. cerevisiae) MAD3 (S. cerevisiae) bub-1 (C. elegans) Bub1 (D. melanogaster) BubR1 (D. melanogaster)
NSD1	ENSG00000165671	AML	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding chromatin binding transcription cofactor activity transcription corepressor activity zinc ion binding histone-lysine N-methyltransferase activity estrogen receptor binding histone methyltransferase activity (H4-K20 specific) retinoic acid receptor binding retinoid X receptor binding thyroid hormone receptor binding histone methyltransferase activity (H3-K36 specific) androgen receptor binding	SET2 (S. cerevisiae)