HIP1 - RB1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HIP1	ENSG00000127946	CMML NSCLC	No drugs in record	epidermal growth factor receptor binding structural constituent of cytoskeleton protein binding clathrin binding clathrin light chain binding phosphatidylinositol-3-phosphate binding phosphatidylinositol binding glutamate receptor binding AP-2 adaptor complex binding clathrin adaptor activity protein homodimerization activity phosphatidylinositol-3,4-bisphosphate binding protein heterodimerization activity actin filament binding phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-4,5-bisphosphate binding high-affinity L-histidine transmembrane transporter activity antiporter activity actin binding phospholipid binding transcription corepressor activity	SLA2 (S. cerevisiae) Hip1 (D. melanogaster)
RB1	ENSG00000139687	retinoblastoma sarcoma breast small cell lung carcinoma	No drugs in record	core promoter binding RNA polymerase II activating transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding kinase binding ubiquitin protein ligase binding identical protein binding androgen receptor binding phosphoprotein binding	lin-35 (C. elegans) Rbf2 (D. melanogaster)