IRS1 - HRAS

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
IRS1	ENSG00000169047	No diseases in record	No drugs in record	signal transducer activity transmembrane receptor protein tyrosine kinase adaptor activity protein kinase C binding Ras guanyl-nucleotide exchange factor activity insulin receptor binding insulin-like growth factor receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH2 domain binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity tRNA binding aminoacyl-tRNA editing activity ATP binding isoleucine-tRNA ligase activity	chico (D. melanogaster)
HRAS	ENSG00000174775	infrequent sarcomas rare other tumour types rhabdomyosarcoma ganglioneuroblastoma bladder	No drugs in record	GTPase activity protein binding GTP binding protein C-terminus binding	RAS1 (S. cerevisiae) RAS2 (S. cerevisiae) let-60 (C. elegans) Ras85D (D. melanogaster)