SPEN - FBXW7

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
SPEN ENSG00000065526 SMZL
adenoid cystic carcinoma
DLBCL

No drugs in record

nucleotide binding
RNA polymerase II transcription factor binding
transcriptional repressor activity, RNA polymerase II transcription factor binding
nucleic acid binding
DNA binding
protein binding
spen (D. melanogaster)
FBXW7 ENSG00000109670 colorectal
endometrial
T-ALL

No drugs in record

ubiquitin-protein transferase activity
protein binding
cyclin binding
protein binding, bridging
ubiquitin protein ligase binding
identical protein binding
phosphothreonine residue binding
ubiquitin-protein transferase activator activity
MET30 (S. cerevisiae)
sel-10 (C. elegans)
ago (D. melanogaster)