HLTF - ABL1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HLTF	ENSG00000071794	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding helicase activity protein binding ATP binding zinc ion binding ligase activity ATPase activity ubiquitin protein ligase binding ubiquitin protein ligase activity	RAD5 (S. cerevisiae)
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)