FBXW7 - ADAM17

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FBXW7	ENSG00000109670	colorectal endometrial T-ALL	No drugs in record	ubiquitin-protein transferase activity protein binding cyclin binding protein binding, bridging ubiquitin protein ligase binding identical protein binding phosphothreonine residue binding ubiquitin-protein transferase activator activity	MET30 (S. cerevisiae) sel-10 (C. elegans) ago (D. melanogaster)
ADAM17	ENSG00000151694	No diseases in record	No drugs in record	metalloendopeptidase activity Notch binding interleukin-6 receptor binding integrin binding protein binding metallopeptidase activity SH3 domain binding PDZ domain binding metal ion binding	Tace (D. melanogaster)