ITCH - YWHAE

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ITCH	ENSG00000078747	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding ubiquitin-like protein transferase activity ribonucleoprotein complex binding CXCR chemokine receptor binding ubiquitin protein ligase activity	RSP5 (S. cerevisiae) wwp-1 (C. elegans) Su(dx) (D. melanogaster)
YWHAE	ENSG00000108953	endometrial stromal sarcoma	No drugs in record	protein binding potassium channel regulator activity enzyme binding protein domain specific binding MHC class II protein complex binding ubiquitin protein ligase binding histone deacetylase binding ion channel binding protein heterodimerization activity phosphoserine residue binding phosphoprotein binding cadherin binding involved in cell-cell adhesion	BMH1 (S. cerevisiae) BMH2 (S. cerevisiae) M117.3 (C. elegans) 14-3-3epsilon (D. melanogaster)