AGO2 - LRRK2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
AGO2	ENSG00000123908	No diseases in record	No drugs in record	RNA 7-methylguanosine cap binding RNA polymerase II core binding core promoter binding double-stranded RNA binding single-stranded RNA binding mRNA binding translation initiation factor activity endoribonuclease activity protein binding protein C-terminus binding bidentate ribonuclease III activity siRNA binding miRNA binding metal ion binding endoribonuclease activity, cleaving siRNA-paired mRNA endoribonuclease activity, cleaving miRNA-paired mRNA mRNA cap binding	alg-1 (C. elegans) alg-2 (C. elegans) AGO1 (D. melanogaster)
LRRK2	ENSG00000188906	No diseases in record	No drugs in record	SNARE binding glycoprotein binding actin binding GTPase activity protein kinase activity protein serine/threonine kinase activity MAP kinase kinase activity GTPase activator activity protein binding ATP binding GTP binding microtubule binding tubulin binding kinase activity Rho GTPase binding syntaxin-1 binding receptor signaling complex scaffold activity clathrin binding GTP-dependent protein kinase activity peroxidase inhibitor activity co-receptor binding identical protein binding protein homodimerization activity ion channel binding protein kinase A binding beta-catenin destruction complex binding	MEK1 (S. cerevisiae)