APC - LRRK2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
APC	ENSG00000134982	colorectal pancreatic desmoid hepatoblastoma glioma other CNS	No drugs in record	protein binding beta-catenin binding microtubule binding protein kinase regulator activity protein kinase binding gamma-catenin binding microtubule plus-end binding cadherin binding	apr-1 (C. elegans) Apc2 (D. melanogaster) Apc (D. melanogaster)
LRRK2	ENSG00000188906	No diseases in record	No drugs in record	SNARE binding glycoprotein binding actin binding GTPase activity protein kinase activity protein serine/threonine kinase activity MAP kinase kinase activity GTPase activator activity protein binding ATP binding GTP binding microtubule binding tubulin binding kinase activity Rho GTPase binding syntaxin-1 binding receptor signaling complex scaffold activity clathrin binding GTP-dependent protein kinase activity peroxidase inhibitor activity co-receptor binding identical protein binding protein homodimerization activity ion channel binding protein kinase A binding beta-catenin destruction complex binding	MEK1 (S. cerevisiae)