TOP2B - BAP1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
TOP2B ENSG00000077097

No diseases in record

ETOPOSIDE
TENIPOSIDE
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA binding, bending
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
BAP1 ENSG00000163930 uveal melanoma
breast
NSCLC
RCC
mesothelioma

No drugs in record

chromatin binding
thiol-dependent ubiquitin-specific protease activity
protein binding
peptidase activity
calypso (D. melanogaster)