TOP2B - SMC6

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
SMC6	ENSG00000163029	No diseases in record	No drugs in record	protein binding ATP binding ubiquitin protein ligase binding SUMO transferase activity damaged DNA binding nucleotide binding double-stranded DNA-dependent ATPase activity	SMC6 (S. cerevisiae) smc-6 (C. elegans) C23H4.6 (C. elegans) jnj (D. melanogaster)