TOP2B - DNM2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
DNM2	ENSG00000079805	T-ALL	No drugs in record	GTPase activity protein binding GTP binding microtubule binding SH3 domain binding enzyme binding protein kinase binding D2 dopamine receptor binding protein complex binding phosphatidylinositol 3-kinase regulatory subunit binding WW domain binding nitric-oxide synthase binding	VPS1 (S. cerevisiae) dyn-1 (C. elegans) shi (D. melanogaster)