TOP2B - MCM3

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
MCM3	ENSG00000112118	No diseases in record	No drugs in record	DNA binding DNA helicase activity protein binding ATP binding single-stranded DNA-dependent ATP-dependent DNA helicase activity helicase activity DNA replication origin binding chromatin binding ATPase activity hydrolase activity nucleotide binding 3'-5' DNA helicase activity ATP-dependent DNA helicase activity	MCM3 (S. cerevisiae)