TOP2B - USP21

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
USP21	ENSG00000143258	No diseases in record	No drugs in record	transcription coactivator activity thiol-dependent ubiquitin-specific protease activity protein binding cysteine-type peptidase activity NEDD8-specific protease activity metal ion binding	DOA4 (S. cerevisiae) UBP5 (S. cerevisiae)