CHD8 - FBXW7

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CHD8	ENSG00000100888	No diseases in record	No drugs in record	p53 binding DNA binding DNA helicase activity chromatin binding protein binding ATP binding beta-catenin binding DNA-dependent ATPase activity methylated histone binding histone binding armadillo repeat domain binding	CHD1 (S. cerevisiae) chd-7 (C. elegans)
FBXW7	ENSG00000109670	colorectal endometrial T-ALL	No drugs in record	ubiquitin-protein transferase activity protein binding cyclin binding protein binding, bridging ubiquitin protein ligase binding identical protein binding phosphothreonine residue binding ubiquitin-protein transferase activator activity	MET30 (S. cerevisiae) sel-10 (C. elegans) ago (D. melanogaster)