MECOM - FBXW7

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MECOM	ENSG00000085276	AML CML MDS	No drugs in record	DNA binding transcription factor activity, sequence-specific DNA binding protein binding histone-lysine N-methyltransferase activity metal ion binding	COM2 (S. cerevisiae) MSN2 (S. cerevisiae)
FBXW7	ENSG00000109670	colorectal endometrial T-ALL	No drugs in record	ubiquitin-protein transferase activity protein binding cyclin binding protein binding, bridging ubiquitin protein ligase binding identical protein binding phosphothreonine residue binding ubiquitin-protein transferase activator activity	MET30 (S. cerevisiae) sel-10 (C. elegans) ago (D. melanogaster)