SKP1 - IRS1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SKP1	ENSG00000113558	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding beta-catenin binding cullin family protein binding ubiquitin protein ligase activity DNA replication origin binding DNA binding	SKP1 (S. cerevisiae) skr-2 (C. elegans) skr-1 (C. elegans) skr-17 (C. elegans) skr-9 (C. elegans) skr-8 (C. elegans) skr-7 (C. elegans) skr-18 (C. elegans) skr-10 (C. elegans) skr-13 (C. elegans) skr-12 (C. elegans) SkpA (D. melanogaster) SkpE (D. melanogaster) SkpB (D. melanogaster) SkpF (D. melanogaster) SkpC (D. melanogaster) SkpD (D. melanogaster)
IRS1	ENSG00000169047	No diseases in record	No drugs in record	signal transducer activity transmembrane receptor protein tyrosine kinase adaptor activity protein kinase C binding Ras guanyl-nucleotide exchange factor activity insulin receptor binding insulin-like growth factor receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH2 domain binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity tRNA binding aminoacyl-tRNA editing activity ATP binding isoleucine-tRNA ligase activity	chico (D. melanogaster)