RB1 - WT1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RB1	ENSG00000139687	retinoblastoma sarcoma breast small cell lung carcinoma	No drugs in record	core promoter binding RNA polymerase II activating transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding kinase binding ubiquitin protein ligase binding identical protein binding androgen receptor binding phosphoprotein binding	lin-35 (C. elegans) Rbf2 (D. melanogaster)
WT1	ENSG00000184937	Wilms tumour desmoplastic small round cell tumour	No drugs in record	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding RNA binding protein binding zinc ion binding double-stranded methylated DNA binding sequence-specific DNA binding transcription regulatory region DNA binding hemi-methylated DNA-binding C2H2 zinc finger domain binding	MIG1 (S. cerevisiae) MIG2 (S. cerevisiae) MIG3 (S. cerevisiae)