EP300 - HDAC2

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
EP300 ENSG00000100393 colorectal
breast
pancreatic
AML
ALL
DLBCL

No drugs in record

RNA polymerase II core promoter sequence-specific DNA binding
core promoter binding
RNA polymerase II activating transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
transcription coactivator activity
histone acetyltransferase activity
lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
protein binding
beta-catenin binding
protein C-terminus binding
transcription factor binding
zinc ion binding
acetyltransferase activity
transferase activity, transferring acyl groups
chromatin DNA binding
activating transcription factor binding
peptide N-acetyltransferase activity
nuclear hormone receptor binding
androgen receptor binding
pre-mRNA intronic binding
BDF1 (S. cerevisiae)
BDF2 (S. cerevisiae)
nej (D. melanogaster)
HDAC2 ENSG00000196591

No diseases in record

BELINOSTAT
PANOBINOSTAT
ROMIDEPSIN
VORINOSTAT
core promoter binding
RNA polymerase II repressing transcription factor binding
chromatin binding
histone deacetylase activity
protein binding
transcription factor binding
deacetylase activity
enzyme binding
heat shock protein binding
NAD-dependent histone deacetylase activity (H3-K14 specific)
protein deacetylase activity
sequence-specific DNA binding
NF-kappaB binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
nucleosomal DNA binding
RPD3 (S. cerevisiae)
hda-1 (C. elegans)
hda-3 (C. elegans)