DIS3 - HDAC2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DIS3	ENSG00000083520	No diseases in record	No drugs in record	3'-5'-exoribonuclease activity RNA binding endonuclease activity guanyl-nucleotide exchange factor activity protein binding tRNA binding endoribonuclease activity nuclease activity exonuclease activity hydrolase activity nucleic acid binding exoribonuclease activity Ran GTPase binding ribonuclease activity	DIS3 (S. cerevisiae) dis-3 (C. elegans) Dis3 (D. melanogaster)
HDAC2	ENSG00000196591	No diseases in record	BELINOSTAT PANOBINOSTAT ROMIDEPSIN VORINOSTAT	core promoter binding RNA polymerase II repressing transcription factor binding chromatin binding histone deacetylase activity protein binding transcription factor binding deacetylase activity enzyme binding heat shock protein binding NAD-dependent histone deacetylase activity (H3-K14 specific) protein deacetylase activity sequence-specific DNA binding NF-kappaB binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	RPD3 (S. cerevisiae) hda-1 (C. elegans) hda-3 (C. elegans)