FBXW7 - VAV3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FBXW7	ENSG00000109670	colorectal endometrial T-ALL	No drugs in record	ubiquitin-protein transferase activity protein binding cyclin binding protein binding, bridging ubiquitin protein ligase binding identical protein binding phosphothreonine residue binding ubiquitin-protein transferase activator activity	MET30 (S. cerevisiae) sel-10 (C. elegans) ago (D. melanogaster)
VAV3	ENSG00000134215	No diseases in record	No drugs in record	SH3/SH2 adaptor activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity epidermal growth factor receptor binding protein binding Rac guanyl-nucleotide exchange factor activity metal ion binding	CDC24 (S. cerevisiae)