PPM1A - SMAD7

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PPM1A	ENSG00000100614	No diseases in record	No drugs in record	magnesium ion binding protein serine/threonine phosphatase activity signal transducer activity protein binding manganese ion binding calmodulin-dependent protein phosphatase activity R-SMAD binding	PTC2 (S. cerevisiae) PTC3 (S. cerevisiae)
SMAD7	ENSG00000101665	No diseases in record	No drugs in record	transcription factor activity, sequence-specific DNA binding protein binding collagen binding beta-catenin binding transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity ubiquitin protein ligase binding type I transforming growth factor beta receptor binding transcription regulatory region DNA binding metal ion binding activin binding I-SMAD binding	daf-14 (C. elegans) daf-8 (C. elegans) Dad (D. melanogaster)