HMGB2 - GRB2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HMGB2	ENSG00000164104	No diseases in record	No drugs in record	four-way junction DNA binding enhancer sequence-specific DNA binding DNA binding damaged DNA binding double-stranded DNA binding single-stranded DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding drug binding DNA binding, bending protein domain specific binding chemoattractant activity transcription regulatory region DNA binding non-sequence-specific DNA binding, bending RAGE receptor binding supercoiled DNA binding	NHP6A (S. cerevisiae) NHP6B (S. cerevisiae) hmg-1.2 (C. elegans)
GRB2	ENSG00000177885	No diseases in record	No drugs in record	phosphotyrosine residue binding SH3/SH2 adaptor activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding neurotrophin TRKA receptor binding protein binding 1-phosphatidylinositol-3-kinase activity SH3 domain binding protein kinase binding protein phosphatase binding identical protein binding insulin receptor substrate binding ephrin receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	sem-5 (C. elegans)